A hormonal association between estrogen metabolism and proliferative thyroid disease.

@article{Chan2006AHA,
  title={A hormonal association between estrogen metabolism and proliferative thyroid disease.},
  author={Edwin K Chan and Daniel W. Sepkovic and Helen J Yoo Bowne and Guo Yu and Stimson Pryor Schantz},
  journal={Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery},
  year={2006},
  volume={134 6},
  pages={893-900}
}
OBJECTIVE To illustrate a relationship between proliferative thyroid disease and estrogen metabolism through the analysis of urinary estrogen metabolites. STUDY DESIGN AND SETTING Case-control study of 49 subjects with proliferative thyroid disorders and matching them to 49 controls. Urinary estrogen metabolite ratios were obtained, measuring 2-hydroxyestrone, an anti-proliferative metabolite, to 16alpha-hydroxyestrone, a proliferative metabolite. The patients were stratified into low (0 to 1… CONTINUE READING

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