A homogeneous single-label time-resolved fluorescence cAMP assay.

Abstract

G-protein-coupled receptors (GPCRs) are an important class of pharmaceutical drug targets. Functional high-throughput GPCR assays are needed to test an increasing number of synthesized novel drug compounds and their function in signal transduction processes. Measurement of changes in the cyclic adenosine monophosphate (cAMP) concentration is a widely used… (More)
DOI: 10.1177/1087057110397356

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