A homeobox protein, prox1, is involved in the differentiation, proliferation, and prognosis in hepatocellular carcinoma.

@article{Shimoda2006AHP,
  title={A homeobox protein, prox1, is involved in the differentiation, proliferation, and prognosis in hepatocellular carcinoma.},
  author={Masayuki Shimoda and Meiko Takahashi and Takanobu Yoshimoto and Tomoya Kono and Iwao Ikai and Hajime Kubo},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2006},
  volume={12 20 Pt 1},
  pages={6005-11}
}
PURPOSE It has been shown that a lymphatic differentiation master gene, prox1, also plays an essential role in fetal hepatocyte migration. Its expression is detected in embryonic hepatoblasts and in adult hepatocytes. Hepatoma cells are similar to embryonic hepatoblasts to a certain extent because they both proliferate and invade the surrounding tissue. To address the possibility that Prox1 may be involved in the tumorigenesis of hepatocellular carcinoma (HCC), human clinical samples were… CONTINUE READING
47 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 47 extracted citations

Similar Papers

Loading similar papers…