A homeobox gene of the Antennapedia class is required for human adult erythropoiesis.

@article{Takeshita1993AHG,
  title={A homeobox gene of the Antennapedia class is required for human adult erythropoiesis.},
  author={Kenichi Takeshita and Jacques A. Bollekens and Naoki Hijiya and Mariusz Z. Ratajczak and F. H. Ruddle and Alan M. Gewirtz},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1993},
  volume={90 8},
  pages={
          3535-8
        }
}
In this report we investigate the role of homeobox genes of the Antennapedia class in adult erythropoiesis, the process by which erythrocytes are formed in the bone marrow. We initially identified Hox genes expressed in mouse erythroleukemia cells by a PCR technique using degenerate primers capable of detecting most of the known genes in Hox clusters 1-4. Four different transcripts, Hox-3.3, -3.5, -3.6, and -4.3 were identified. An antisense oligonucleotide directed against HOX3C (human… CONTINUE READING
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