A history of poly A sequences: from formation to factors to function.

  • Mary Edmonds
  • Published 2002 in
    Progress in nucleic acid research and molecular…

Abstract

Biological polyadenylation, first recognized as an enzymatic activity, remained an orphan enzyme until poly A sequences were found on the 3' ends of eukarvotic mRNAs. Their presence in bacteria viruses and later in archeae (ref. 338) established their universality. The lack of compelling evidence for a specific function limited attention to their cellular… (More)

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Cite this paper

@article{Edmonds2002AHO, title={A history of poly A sequences: from formation to factors to function.}, author={Mary Edmonds}, journal={Progress in nucleic acid research and molecular biology}, year={2002}, volume={71}, pages={285-389} }