A history of investigation on the mood stabilizing effect of carbamazepine in Japan

@article{kuma2002AHO,
  title={A history of investigation on the mood stabilizing effect of carbamazepine in Japan},
  author={Teruo Ōkuma and Akira Kishimoto},
  journal={Psychiatry and Clinical Neurosciences},
  year={2002},
  volume={52}
}
Abstract A history of investigation on the antimanic and prophylactic effects of carbamazepine in Japan is described. Following the initial open trials in the early 1970s in which the antimanic and prophylactic effects of carbamazepine were indicated for the first time in the world, the mood stabilizing effect was confirmed by the double blind studies which were performed with a multi‐institutional cooperation in Japan in the late 1970s. During the course of the double blind trials, the problem… Expand
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References

SHOWING 1-10 OF 71 REFERENCES
Comparison of the antimanic efficacy of carbamazepine and chlorpromazine: A double-blind controlled study
TLDR
Improvements in basic mood, insomnia, headache and lassitude, and diurnal fluctuations of mood tended to be characteristic of carbamazepine efficacy for mania compared with the effects of chlorpromazine. Expand
Use of Carbamazepine in Acute Psychosis: A Controlled Study
TLDR
Results confirm that CBZ is a valid alternative to lithium in the treatment of acute psychosis and no clinically relevant differences were found between the two groups. Expand
Comparison of the antimanic efficacy of carbamazepine and lithium carbonate by double-blind controlled study.
TLDR
While the shortcomings of the present study limit the interpretation of the data, it may be suggested that the usefulness of CBZ as a drug for the treatment of manic states is comparable to that of Li. Expand
A preliminary double-blind study on the efficacy of carbamazepine in prophylaxis of manic-depressive illness
TLDR
A preliminary double-blind controlled study on the prophylactic effect of carbamazepine on recurrent manic-depressive psychotics was conducted with 22 patients using an inert placebo in ten subjects as a control drug, and it is suggested that carbamazepsine is a useful drug for theProphylaxis of manic- Depressive illness. Expand
Comparison of efficacy of lithium carbonate and chlorpromazine in mania. Report of collaborative study group on treatment of mania in Japan.
TLDR
Onset of the therapeutic effect of lithium carbonate was within ten days of medication in 65% of patients, significantly faster than with chlorpromazine. Expand
The comparative efficacy and safety of carbamazepine versus lithium: a randomized, double-blind 3-year trial in 83 patients.
TLDR
Both drugs were effective in two thirds of the patients and appeared about equal in most outcome measures, except for a significantly higher dropout rate for patients with mood-incongruent psychotic features who were assigned to the lithium group. Expand
Treatment of depression with clonazepam
TLDR
It is thought that clonazepam might be useful as an antidepressant for patients in whom conventional antidepressant treatment are contraindicated. Expand
Anti‐Manic and Prophylactic Effects of Carbamazepine (Tegretol) on Manic Depressive Psychosis A Preliminary Report
TLDR
The prophylactic effect on MDP ofCAZP did not parallel that of lithium salt, but CAZP may be effective on cases which did not respond to lithium and vice versa. Expand
A double‐blind study of adjunctive carbamazepine versus placebo on excited states of schizophrenic and schizoaffective disorders
TLDR
The results suggest that carbamazepine, when used in combination with neuroleptics, is a useful drug for the treatment of excited states of patients with schizophrenic and schizoaffective disorders. Expand
Carbamazepine in manic-depressive illness: a new treatment.
The authors evaluated carbamazepine (Tegretol), a drug of choice for treatment of temporal lobe epilepsy, in a double-blind placebo-controlled trial in patients with manic-depressive illness. SevenExpand
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1
2
3
4
5
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