A historical perspective of anthracycline cardiotoxicity.

  title={A historical perspective of anthracycline cardiotoxicity.},
  author={Michael S. Ewer and Daniel Von Hoff and Robert S Benjamin},
  journal={Heart failure clinics},
  volume={7 3},
Anthracyclines remain important agents in the treatment of solid and hematological malignancy. Early experience with these drugs reported cardiac failure as an adverse event. Later, clinical recognition of cell injury at the time of administration was appreciated. This article explores the evolution of our understanding about anthracycline-associated cardiotoxicity, including the various strategies for the pretreatment assessment of patients for whom anthracyclines are contemplated, the… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 19 extracted citations


Publications referenced by this paper.
Showing 1-10 of 42 references

Trastuzumab-induced cardiotoxicity: clinical and prognostic implication of troponin I elevation

  • D Cardinale, A Colombo, R Torrisi
  • J Clin Oncol 2010;28:3910–6
  • 2010
1 Excerpt

BCIRG 006 phase III trial comparing AC-T with AC-TH and with TCH. In: The adjuvant treatment of HER2-amplified early breast cancer patients: third planned efficacy analysis

  • D Slamon, W Eiermann, N Robert
  • San Antonio Breast Cancer Symposium. San Antonio…
  • 2009
1 Excerpt

Similar Papers

Loading similar papers…