A historical perspective of anthracycline cardiotoxicity.

@article{Ewer2011AHP,
  title={A historical perspective of anthracycline cardiotoxicity.},
  author={Michael S. Ewer and Daniel Von Hoff and Robert S Benjamin},
  journal={Heart failure clinics},
  year={2011},
  volume={7 3},
  pages={363-72}
}
Anthracyclines remain important agents in the treatment of solid and hematological malignancy. Early experience with these drugs reported cardiac failure as an adverse event. Later, clinical recognition of cell injury at the time of administration was appreciated. This article explores the evolution of our understanding about anthracycline-associated cardiotoxicity, including the various strategies for the pretreatment assessment of patients for whom anthracyclines are contemplated, the… CONTINUE READING

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