A histopathologic and morphometric differentiation of nerves in optic nerve hypoplasia and Leber hereditary optic neuropathy.

@article{Saadati1998AHA,
  title={A histopathologic and morphometric differentiation of nerves in optic nerve hypoplasia and Leber hereditary optic neuropathy.},
  author={Hamid Saadati and Hugo Y. Hsu and Katherine Bristow Heller and Alfredo Arrigo Sadun},
  journal={Archives of ophthalmology},
  year={1998},
  volume={116 7},
  pages={911-6}
}
OBJECTIVES To characterize and quantitate optic nerve histopathologic and morphometric differences between optic nerve hypoplasia (ONH) as an early and congenital form of intrinsic axonal loss and Leber hereditary optic neuropathy (LHON) as a late and acquired form of intrinsic axonal loss. MATERIALS AND METHODS Optic nerves from 3 sources were examined: a 42-year-old healthy woman (control), a 53-year-old woman with ONH diagnosed postmortem, and a 74-year-old woman with LHON. The optic… CONTINUE READING

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Morphologi - cal findings in the visual system in a case of Leber ’ s hereditary optic neuropa

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Morphological findings in the visual system in a case of Leber’s hereditary optic neuropathy

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