A histological evaluation of the involvement of Bio-Oss in osteoblastic differentiation and matrix synthesis.

@article{Tapety2004AHE,
  title={A histological evaluation of the involvement of Bio-Oss in osteoblastic differentiation and matrix synthesis.},
  author={Fabricio I Tapety and Norio Amizuka and Katsumi Uoshima and Shuichi Nomura and Takeyasu Maeda},
  journal={Clinical oral implants research},
  year={2004},
  volume={15 3},
  pages={
          315-24
        }
}
This study was designed to investigate the responses of bone cells to a deproteinized bovine bone material, Bio-Oss (Geistlich-Pharma, Wolhunsen, Switzerland), which was grafted in artificial bone defects of rat femurs. Standardized bone defects in the cortical bone of the right femurs were grafted with Bio-Oss particles. Narrow penetrations were prepared on the bottom of the cavity, enabling osteogenic cells to migrate from the bone marrow. A defect in the left femur without Bio-Oss was used… CONTINUE READING
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