A histological, histochemical and biochemical study of the macroscopically normal white matter in multiple sclerosis

@article{Allen1979AHH,
  title={A histological, histochemical and biochemical study of the macroscopically normal white matter in multiple sclerosis},
  author={I. Allen and S. McKeown},
  journal={Journal of the Neurological Sciences},
  year={1979},
  volume={41},
  pages={81-91}
}
In a combined histological, biochemical and histochemical study of the macroscopically normal white matter in multipe sclerosis 72% of samples were histologically abnormal. The significance of this fact in the interpretation of previous biochemical studies and in the design of future studies is discussed. The present study showed a significant elevation of the lysosomal enzyme beta-glucosaminidase in the microscopically normal white matter in MS as compared with controls. Studies on lysosomes… Expand
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