A hint to search for metalloproteins in gene banks

@article{Andreini2004AHT,
  title={A hint to search for metalloproteins in gene banks},
  author={Claudia Andreini and Ivano Bertini and Antonio Rosato},
  journal={Bioinformatics},
  year={2004},
  volume={20 9},
  pages={
          1373-80
        }
}
MOTIVATION With the advent of genome sequencing, a huge database of protein primary sequences has been accumulating. In parallel, a number of tools to investigate and expand upon this information, e.g. reconstructing and building relationships between protein families and superfamilies, have been developed. Metalloproteins are proteins capable of binding one or more metal ions, which are required for their biological function or for regulation of their activities or for structural purposes… CONTINUE READING

Figures, Tables, Results, and Topics from this paper.

Key Quantitative Results

  • It appears that copper-binding capabilities are identified with a confidence >90% when the percentage of identical amino acids aligned around the MBP by PHI-BLAST is at least 20% with respect to the entire protein domain length.

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