A highly sensitive high-performance liquid chromatography-mass spectrometry method for quantification of fludarabine triphosphate in leukemic cells.

Abstract

A high-performance liquid chromatography (HPLC)-mass spectrometry (MS) method has been developed for the analysis of 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-triphosphate (F-ara-ATP) from biological samples. Quantification is carried out by selected ion monitoring of the parent ion. Baseline separation of the monophosphate (F-ara-AMP) and diphosphate (F… (More)

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@article{Kalhorn2005AHS, title={A highly sensitive high-performance liquid chromatography-mass spectrometry method for quantification of fludarabine triphosphate in leukemic cells.}, author={Thomas F. Kalhorn and Aaron G. Ren and John T. Slattery and Jeannine S. McCune and Joanne H. Wang}, journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences}, year={2005}, volume={820 2}, pages={243-50} }