A highly polymorphic locus in human DNA.

@article{Wyman1980AHP,
  title={A highly polymorphic locus in human DNA.},
  author={Arlene R. Wyman and R. White},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1980},
  volume={77 11},
  pages={6754-8}
}
A locus in the human genome, not associated with any specific gene, has been found to be a site of restriction fragment length polymorphism. The polymorphism was found by hybridizing a 16-kilobase-pair segment of single-copy human DNA, selected from the human genome library cloned in phage lambda CH4A, to a Southern transfer of total human DNA digested with EcoRI. DNAs from a number of individuals from within Mormon pedigrees as well as random individuals have been examined. The locus is highly… CONTINUE READING

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Cancer Incidence in Defined Populatins (Cold Spring Harbor Laboratory, Cold Spring Harbor, NY)

D. Botstein, White, M. R. L Skolnick, R. W. Davis
Banbury Report No • 1980

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