A highly distinctive mechanical property found in the majority of human promoters and its transcriptional relevance

Abstract

A recent study revealed that TATA boxes and initiator sequences have a common anomalous mechanical property, i.e. they comprise distinctive flexible and rigid sequences when compared with the other parts of the promoter region. In the present study, using the flexibility parameters from two different models, we calculated the average flexibility profiles of… (More)

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5 Figures and Tables