A higher dose of vancomycin in continuous infusion is needed in critically ill patients.

Abstract

Compared with intermittent infusion, continuous infusion of vancomycin is cheaper and logistically more convenient, achieves target concentrations faster, results in less variability in serum vancomycin concentrations, requires less therapeutic drug monitoring and causes less nephrotoxicity. Given that critically ill patients may develop very large volumes… (More)
DOI: 10.1016/j.ijantimicag.2010.09.004

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