A high-throughput colorimetric assay for detection of Schistosoma mansoni viability based on the tetrazolium salt XTT

@inproceedings{Aguiar2017AHC,
  title={A high-throughput colorimetric assay for detection of Schistosoma mansoni viability based on the tetrazolium salt XTT},
  author={Pedro Henrique Nascimento Aguiar and N{\'u}bia Monteiro Gonçalves Soares Fernandes and Carlos L Zani and Marina de Moraes Mour{\~a}o},
  booktitle={Parasites & Vectors},
  year={2017}
}
BackgroundSchistosoma mansoni is a trematode parasite that causes schistosomiasis, one of the most prevalent neglected tropical diseases, leading to the loss of 2.6 million disability-adjusted life years. Praziquantel is the only drug available, and new drugs are required. The most common strategy in schistosomiasis drug discovery is the use of the schistosomula larval-stage for a pre-screen in drug sensitivity assays. However, assessing schistosomula viability by microscopy has always been a… CONTINUE READING
BETA
1
Twitter Mention

Similar Papers

Figures, Tables, and Topics from this paper.

References

Publications referenced by this paper.
SHOWING 1-10 OF 34 REFERENCES

HTS Assay Validation

VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Selective inhibition of BET bromodomains

VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL