A high-speed magnetic tweezer beyond 10,000 frames per second.
@article{Lansdorp2013AHM,
title={A high-speed magnetic tweezer beyond 10,000 frames per second.},
author={Bob M. Lansdorp and Shawn J Tabrizi and Andrew Dittmore and Omar A. Saleh},
journal={The Review of scientific instruments},
year={2013},
volume={84 4},
pages={
044301
}
}The magnetic tweezer is a single-molecule instrument that can apply a constant force to a biomolecule over a range of extensions, and is therefore an ideal tool to study biomolecules and their interactions. However, the video-based tracking inherent to most magnetic single-molecule instruments has traditionally limited the instrumental resolution to a few nanometers, above the length scale of single DNA base-pairs. Here we have introduced superluminescent diode illumination and high-speed…
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