A high specificity and affinity interaction with serum albumin stimulates an anion conductance in malaria-infected erythrocytes.

@article{Duranton2008AHS,
  title={A high specificity and affinity interaction with serum albumin stimulates an anion conductance in malaria-infected erythrocytes.},
  author={Christophe Duranton and Val{\'e}rie Tanneur and Camelia Lang and Verena B. Brand and Saisudha Koka and Ravi S. Kasinathan and Martina Dorsch and Hans J{\"u}rgen Hedrich and Stefan Baumeister and Klaus R. Lingelbach and Florian Lang and Stephan M Huber},
  journal={Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology},
  year={2008},
  volume={22 5-6},
  pages={395-404}
}
The intraerythrocytic development of P. falciparum induces New Permeability Pathways (NPP) in the membrane of the parasitized erythrocyte which provide the parasite with nutrients, adjust the erythrocyte electrolyte composition to the needs of the parasite, and dispose of metabolic waste products and osmolytes. Patch-clamp recordings identified inwardly and outwardly rectifying (OR) anion conductances in the host erythrocyte membrane as electrophysiological correlate of the NPP. The OR… CONTINUE READING