A high serum matrix metalloproteinase-2 level is associated with an adverse prognosis in node-positive breast carcinoma.

@article{Lepp2004AHS,
  title={A high serum matrix metalloproteinase-2 level is associated with an adverse prognosis in node-positive breast carcinoma.},
  author={Sirpa Lepp{\"a} and Tiina Saarto and Leena K Vehmanen and Carl Blomqvist and Inkeri Elomaa},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2004},
  volume={10 3},
  pages={1057-63}
}
PURPOSE The aim of this study was to determine whether serum matrix metalloproteinase (MMP) -2 and MMP-9 levels could predict overall and disease-free survival in primary node-positive breast cancer. EXPERIMENTAL DESIGN MMP-2 and MMP-9 levels were quantitatively measured in serum after surgery from 133 patients with primary node-positive breast cancer using enzyme-linked immunoassays. All of the patients received adjuvant therapy, postmenopausal endocrine treatment (tamoxifen or toremifen for… CONTINUE READING

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