A high prevalence of cytomegalovirus antigenaemia in patients with moderate to severe chronic plaque psoriasis: an association with systemic tumour necrosis factor alpha overexpression.

@article{Asadullah1999AHP,
  title={A high prevalence of cytomegalovirus antigenaemia in patients with moderate to severe chronic plaque psoriasis: an association with systemic tumour necrosis factor alpha overexpression.},
  author={Khusru Asadullah and Susanna Proesch and Heike Audring and I B{\"u}ttnerova and H. D. Volk and Wolfram Sterry and W D Doecke},
  journal={The British journal of dermatology},
  year={1999},
  volume={141 1},
  pages={94-102}
}
Microbiological aspects are considered to be of pathophysiological importance in psoriasis, but there has so far been no information regarding cytomegalovirus (CMV) infection. This is of interest due to the high prevalence of latent infection in the general population, the frequent reactivation in inflammatory diseases, and the immunomodulating capacity of CMV. To detect active infection we analysed CMV antigen expression of peripheral blood mononuclear cells (PBMC) from psoriatic patients (n… CONTINUE READING