A high-powered view of the filtration barrier.

  title={A high-powered view of the filtration barrier.},
  author={J{\'a}nos Peti-Peterdi and Arnold Sipos},
  journal={Journal of the American Society of Nephrology : JASN},
  volume={21 11},
Multiphoton excitation fluorescence microscopy is a powerful noninvasive imaging technique for the deep optical sectioning of living tissues. Its application in several intact tissues is a significant advance in our understanding of organ function, including renal pathophysiological mechanisms. The glomerulus, the filtering unit in the kidney, is one good example of a relatively inaccessible and complex structure, with cell types that are otherwise difficult to study at high resolution in their… CONTINUE READING
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