A high potency nonformylated peptide agonist for the phagocyte N- formylpeptide chemotactic receptor

Abstract

Analysis of synthetic tri- and tetrapeptides has previously indicated that N-formylation is required for high biological activity when they react with the phagocyte N-formylpeptide receptor, suggesting that the natural ligand for the receptor is from bacterial and/or mitochondrial sources. To explore this requirement further, we synthesized the pentapeptide… (More)

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Cite this paper

@article{Gao1994AHP, title={A high potency nonformylated peptide agonist for the phagocyte N- formylpeptide chemotactic receptor}, author={J. L. Gao and E. Becker and Rachel Freer and Natesa Muthukumaraswamy and Patricia Murphy}, journal={The Journal of Experimental Medicine}, year={1994}, volume={180}, pages={2191 - 2197} }