A high level of estrogen-stimulated proteins selects breast cancer patients treated with adjuvant endocrine therapy with good prognosis.

@article{Weischenfeldt2017AHL,
  title={A high level of estrogen-stimulated proteins selects breast cancer patients treated with adjuvant endocrine therapy with good prognosis.},
  author={Katrine L H Weischenfeldt and Tove Kirkegaard and Birgitte Bruun Rasmussen and Anita Giobbie-Hurder and Maj-Britt Jensen and Bent Ejlertsen and Anne Elisabeth Lykkesfeldt},
  journal={Acta oncologica},
  year={2017},
  volume={56 9},
  pages={1161-1167}
}
BACKGROUND Adjuvant endocrine therapy has significantly improved survival of estrogen receptor α (ER)-positive breast cancer patients, but around 20% relapse within 10 years. High expression of ER-stimulated proteins like progesterone receptor (PR), Bcl-2 and insulin-like growth factor receptor I (IGF-IR) is a marker for estrogen-driven cell growth… CONTINUE READING