A high-fat diet generates alterations in nuclear receptor expression : Prevention by vitamin A and links with cyclooxygenase-2 and β-catenin

@inproceedings{Delage2005AHD,
  title={A high-fat diet generates alterations in nuclear receptor expression : Prevention by vitamin A and links with cyclooxygenase-2 and β-catenin},
  author={Barbara Delage and C{\'e}line Bairras and Benjamin Buaud and V{\'e}ronique Pallet and Pierrette Cassand},
  year={2005}
}
Epidemiologic studies suggest that intake of high energy from fat, inducing overweight, increases the risk of cancer development and promotes colon carcinogenesis. It is therefore important to understand which parameters are affected early on by a high-fat diet in order to devise and improve protective nutritional strategies. We investigated the effect of high energy/fat intake on colon mucosa of male Wistar rats induced by a single 1,2-dimethylhydrazine (DMH) injection. Aberrant crypt foci… CONTINUE READING