A high-fat diet during rat pregnancy or suckling induces cardiovascular dysfunction in adult offspring.

@article{Khan2005AHD,
  title={A high-fat diet during rat pregnancy or suckling induces cardiovascular dysfunction in adult offspring.},
  author={Imran Y. Khan and Vasia Dekou and Gillian Douglas and Rigmor Jensen and Mark A. Hanson and Lucilla Poston and Paul D Taylor},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2005},
  volume={288 1},
  pages={R127-33}
}
Epidemiological and animal studies suggest that diet-induced epigenetic modifications in early life can contribute to development of the metabolic syndrome in adulthood. We previously reported features of the metabolic syndrome in adult offspring of rats fed a diet rich in animal fat during pregnancy and suckling. We now report a study to compare the relative effects of high-fat feeding during 1) pregnancy and 2) the suckling period in the development of these disorders. As observed previously… CONTINUE READING

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