A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat.

  title={A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat.},
  author={Robert G. Steen and Anne E. Kwitek-Black and Christopher C Glenn and Jo Gullings-Handley and W. C. van Etten and O. Scott Atkinson and David Appel and Simon Twigger and Melanie Muir and Tim Mull and M. Ag{\"u}ero Granados and Mushira Kissebah and Karen E. Russo and Robbin Crane and Magnus Popp and Marc C. Peden and Tara Cox Matise and Donna M. Brown and Jianping Lu and Stephen Kingsmore and Peter J. Tonellato and Steve Rozen and Donna Slonim and Pari Young and Howard J. Jacob},
  journal={Genome research},
  volume={9 6},
          AP1-8, insert
The laboratory rat (Rattus norvegicus) is a key animal model for biomedical research. However, the genetic infrastructure required for connecting phenotype and genotype in the rat is currently incomplete. Here, we report the construction and integration of two genomic maps: a dense genetic linkage map of the rat and the first radiation hybrid (RH) map of the rat. The genetic map was constructed in two F2 intercrosses (SHRSP x BN and FHH x ACI), containing a total of 4736 simple sequence length… CONTINUE READING
Highly Influential
This paper has highly influenced 10 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Highly Cited
This paper has 140 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 90 extracted citations

Characterization of newly developed SSLP markers for the rat

Mammalian Genome • 2000
View 10 Excerpts
Method Support
Highly Influenced

Gene name ambiguity of eukaryotic nomenclatures

Bioinformatics • 2005
View 4 Excerpts
Highly Influenced

140 Citations

Citations per Year
Semantic Scholar estimates that this publication has 140 citations based on the available data.

See our FAQ for additional information.


Publications referenced by this paper.
Showing 1-10 of 23 references

A linkage map of the rat genome derived from three F2 crosses.

Genome research • 1997
View 11 Excerpts
Highly Influenced

An integrated genetic linkage map of the laboratory rat

Mammalian Genome • 1998
View 5 Excerpts
Highly Influenced

A genetic linkage map of the laboratory rat, Rattus norvegicus

Nature Genetics • 1995
View 6 Excerpts
Highly Influenced

Rat gene mapping using PCR-analyzed microsatellites.

Genetics • 1992
View 3 Excerpts
Highly Influenced