A hidden Ising model for ChIP-chip data analysis

@article{Mo2010AHI,
  title={A hidden Ising model for ChIP-chip data analysis},
  author={Qianxing Mo and Faming Liang},
  journal={Bioinformatics},
  year={2010},
  volume={26 6},
  pages={777-83}
}
MOTIVATION Chromatin immunoprecipitation (ChIP) coupled with tiling microarray (chip) experiments have been used in a wide range of biological studies such as identification of transcription factor binding sites and investigation of DNA methylation and histone modification. Hidden Markov models are widely used to model the spatial dependency of ChIP-chip… CONTINUE READING