A heretofore undisclosed crux of Eosinophilia-Myalgia Syndrome: compromised histamine degradation

  title={A heretofore undisclosed crux of Eosinophilia-Myalgia Syndrome: compromised histamine degradation},
  author={M. Smith and R. H. Garrett},
  journal={Inflammation Research},
  • M. Smith, R. H. Garrett
  • Published 2005
  • Chemistry, Medicine
  • Inflammation Research
  • Abstract.In contrast to early epidemiological evidence offering links between eosinophilia-myalgia syndrome (EMS) and microimpurities of L-tryptophan-containing dietary supplements (LTCDS), this account shows why reliance on a finite impurity from one manufacturer is both unnecessary and insufficient to explain the etiology of EMS. Excessive histamine activity has induced blood eosinophilia and myalgia (Greek: mys, muscle + algos, pain). Termination of the multiple actions of histamine is… CONTINUE READING
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