A hepatocellularis carcinoma - A makroszkópiától a molekuláris patológiáig

  title={A hepatocellularis carcinoma - A makroszk{\'o}pi{\'a}t{\'o}l a molekul{\'a}ris patol{\'o}gi{\'a}ig},
  author={Z. Schaff and Ilona Kovalszky and G{\'a}bor Lotz and A. Kiss},
  journal={Orvosi Hetilap},
A hepatocellularis carcinoma (HCC) igen rossz prognozisu daganat, azonban diagnosztikaja es kezelese teruleten az utobbi evekben jelentős előrehaladas tortent. Mindehhez hozzajarult a HCC molekularis patogenezisenek melyebb megismerese. A cirrhosis talajan kialakult HCC praemalignus elvaltozasai a nagy regenerativ nodulus, az alacsony („low”) es magas („high”) fokozatu diszplasztikus nodulus. Mikroszkoposan a WHO trabecularis (micro-, macrotrabecularis), acinaris (pseudoglandularis… Expand
1 Citations
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The major alterations in microRNA expression patterns in liver diseases such as drug- and alcohol-induced Liver diseases, non-alcoholic fatty liver diseases, fibrosis, viral infections (hepatitis), cirrhosis and hepatocellular carcinoma are summarized. Expand


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The current information on the application of GPC3 immunostaining in surgical pathology and cytology is reviewed to show the sensitivity and specificity exceeds both α-fetoprotein and hepatocyte-paraffin1. Expand
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