A hematopoietic perspective on the promiscuity and specificity of Galpha16 signaling.

@article{Su2009AHP,
  title={A hematopoietic perspective on the promiscuity and specificity of Galpha16 signaling.},
  author={Yan Su and Maurice K. C. Ho and Yung Wong},
  journal={Neuro-Signals},
  year={2009},
  volume={17 1},
  pages={71-81}
}
Galpha(16), a member of G(q) subfamily, is expressed exclusively in hematopoietic cells, and its expression is highly modulated during lineage differentiation. Although functional redundancy within G(q) subclass members has been observed in many established models, Galpha(16)possesses unique structural and biochemical properties not shared by other family members. Its broad receptor-coupling capacity and unique downstream binding partners and effectors allow the occurrence of both inositol… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

References

Publications referenced by this paper.
Showing 1-10 of 114 references

Differ - ential involvement of G  16 in CC chemokine - induced stimulation of phospholipase C  , ERK , and chemotaxis

Y Tian, MM Lee, +3 authors YH Wong
Cell Signal • 2008

Activation of heterotrimeric G proteins by Smoothened.

Proceedings of the National Academy of Sciences of the United States of America • 2006

Similar Papers

Loading similar papers…