A hematopoietic growth factor, thrombopoietin, has a proapoptotic role in the brain.

Abstract

Central nervous and hematopoietic systems share developmental features. We report that thrombopoietin (TPO), a stimulator of platelet formation, acts in the brain as a counterpart of erythropoietin (EPO), a hematopoietic growth factor with neuroprotective properties. TPO is most prominent in postnatal brain, whereas EPO is abundant in embryonic brain and… (More)

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Cite this paper

@article{Ehrenreich2005AHG, title={A hematopoietic growth factor, thrombopoietin, has a proapoptotic role in the brain.}, author={Hannelore Ehrenreich and Martin Hasselblatt and Friederike Knerlich and Nico von Ahsen and Sonja Jacob and Swetlana Sperling and Helge Woldt and Katalin Vehmeyer and Klaus-Armin Nave and A L Sir{\'e}n}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2005}, volume={102 3}, pages={862-7} }