A helical flow, circular microreactor for separating and enriching "smart" polymer-antibody capture reagents.

Abstract

We report a mechanistic study of how flow and recirculation in a microreactor can be used to optimize the capture and release of stimuli-responsive polymer-protein reagents on stimuli-responsive polymer-grafted channel surfaces. Poly(N-isopropylacrylamide) (PNIPAAm) was grafted to polydimethylsiloxane (PDMS) channel walls, creating switchable surfaces where… (More)
DOI: 10.1039/c004978f

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