A haplotype study of HLA complex with special reference to the HLA-DR series and to Bf. C2 and glyoxalase I polymorphisms.

@article{Dausset1978AHS,
  title={A haplotype study of HLA complex with special reference to the HLA-DR series and to Bf. C2 and glyoxalase I polymorphisms.},
  author={Jean Dausset and Louis Legrand and Virginia Lepage and Licinio Contu and A. Marcelli-Barge and I Wildloecher and A. Benajam and Tommaso Di Meo and Laurent Degos},
  journal={Tissue antigens},
  year={1978},
  volume={12 4},
  pages={297-307}
}
Fifty-three French families were typed for alleles at seven loci of the HLA complex (HLA-A, -B, -C, -DR, -Bf, -C2 and -GLO) and 212 haplotypes were demonstrated. Eleven recombinations were observed (two A/B, two A/C, two B/Bf, one Bf/D and four D/GLO). The linkage disequilibrium was calculated not only between two alleles (delta) but between three, four...seven alleles (D). In order to compare the intensity of D values in the various haplotypes, the influence of the differences in gene… CONTINUE READING
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