A guide into glycosciences: How chemistry, biochemistry and biology cooperate to crack the sugar code.

@article{Sols2015AGI,
  title={A guide into glycosciences: How chemistry, biochemistry and biology cooperate to crack the sugar code.},
  author={Dolores Sol{\'i}s and Nicolai V. Bovin and Anthony P Davis and Jes{\'u}s Jim{\'e}nez-Barbero and Antonio Romero and Ren{\'e} Roy and Karel Smetana and Hans-Joachim Gabius},
  journal={Biochimica et biophysica acta},
  year={2015},
  volume={1850 1},
  pages={186-235}
}
BACKGROUND The most demanding challenge in research on molecular aspects within the flow of biological information is posed by the complex carbohydrates (glycan part of cellular glycoconjugates). How the 'message' encoded in carbohydrate 'letters' is 'read' and 'translated' can only be unraveled by interdisciplinary efforts. SCOPE OF REVIEW This review provides a didactic step-by-step survey of the concept of the sugar code and the way strategic combination of experimental approaches… CONTINUE READING
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