A group II self-splicing intron from the brown alga Pylaiella littoralis is active at unusually low magnesium concentrations and forms populations of molecules with a uniform conformation.

@article{Costa1997AGI,
  title={A group II self-splicing intron from the brown alga Pylaiella littoralis is active at unusually low magnesium concentrations and forms populations of molecules with a uniform conformation.},
  author={Maria Elvira Loyola Teixeira da Costa and Jamie M Fontaine and Susan Loiseaux-de Go{\"e}r and François Michel},
  journal={Journal of molecular biology},
  year={1997},
  volume={274 3},
  pages={353-64}
}
We have investigated the reactivity of three of the seven group II introns encoded by the mitochondrial genome of the brown alga Pylaiella littoralis. While the first intron in the protein-coding cox1 gene could not be induced to self-splice under any of the conditions tested, the first two introns in the gene encoding the large ribosomal subunit are reactive in vitro and splice primarily by the standard group II two-step transesterification pathway. Intron 2 proved to be of exceptional… CONTINUE READING

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