A group II intron inserted into a bacterial heat-shock operon shows autocatalytic activity and unusual thermostability.

@article{Adamidi2003AGI,
  title={A group II intron inserted into a bacterial heat-shock operon shows autocatalytic activity and unusual thermostability.},
  author={Catherine Adamidi and Olga Fedorova and Anna M Pyle},
  journal={Biochemistry},
  year={2003},
  volume={42 12},
  pages={3409-18}
}
Group II intron RNAs fold into catalytically active structures that catalyze their own self-splicing and subsequent transposition into DNA. Because of their remarkable enzymatic properties, it has been of interest to find new group II introns with novel properties. Here we report the cloning, sequencing, and mechanistic characterization of a new group II intron from the bacterium Azotobacter vinelandii (the AV intron). Although it bears the characteristics of the group IIB1 class, the AV intron… CONTINUE READING