A graph-theoretic approach for the separation of b and y ions in tandem mass spectra

@article{Yan2005AGA,
  title={A graph-theoretic approach for the separation of b and y ions in tandem mass spectra},
  author={Bo Yan and Chongle Pan and Victor Olman and Robert L. Hettich and Ying Xu},
  journal={Bioinformatics},
  year={2005},
  volume={21 5},
  pages={
          563-74
        }
}
MOTIVATION Ion-type identification is a fundamental problem in computational proteomics. Methods for accurate identification of ion types provide the basis for many mass spectrometry data interpretation problems, including (a) de novo sequencing, (b) identification of post-translational modifications and mutations and (c) validation of database search results. RESULTS Here, we present a novel graph-theoretic approach for solving the problem of separating b ions from y ions in a set of tandem… 

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