A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear

@inproceedings{Mann2014AGO,
  title={A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear},
  author={Zo{\"e} F. Mann and Benjamin R. Thiede and Weise Chang and Jung-Bum Shin and Helen Louise May-Simera and Michael Lovett and Jeffrey T. Corwin and Matthew William Kelley},
  booktitle={Nature communications},
  year={2014}
}
The auditory systems of animals that perceive sounds in air are organized to separate sound stimuli into their component frequencies. Individual tones then stimulate mechanosensory hair cells located at different positions on an elongated frequency (tonotopic) axis. During development, immature hair cells located along the axis must determine their tonotopic position in order to generate frequency-specific characteristics. Expression profiling along the developing tonotopic axis of the chick… CONTINUE READING
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