A goal activation approach to the study of executive function: An application to antisaccade tasks

@article{Nieuwenhuis2004AGA,
  title={A goal activation approach to the study of executive function: An application to antisaccade tasks},
  author={Sander Nieuwenhuis and A. Broerse and Marjan M. A. Nielen and Ritske de Jong},
  journal={Brain and Cognition},
  year={2004},
  volume={56},
  pages={198-214}
}

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References

SHOWING 1-10 OF 74 REFERENCES

Intelligence and the Frontal Lobe: The Organization of Goal-Directed Behavior

It is suggested that g is largely a reflection of the control functions of the frontal lobe, and behavior in any task is structured by a set of action constraints or requirements, derived in part from verbal instructions and specified at multiple levels of abstraction.

Control of Cognitive Processes: Attention and Performance XVIII

The progress achieved in fractionating, localizing, and modeling control functions, and in understanding the interaction between stimulus-driven and voluntary control, takes research on control in the mind/brain to a new level of sophistication.

The effect of fixation condition manipulations on antisaccade performance in schizophrenia: studies of diagnostic specificity

The data suggest that schizophrenia patients are adequately engaged in and understand the antisaccade task and that increased antisaccades error rates may index a liability for schizophrenia within a subset of families.

Abnormalities of internally generated saccades in obsessive–compulsive disorder

The results suggest that patients with OCD have an abnormality in guiding behaviour on the basis of an internal representation of the task goal, rather than a problem with inhibiting reflexive behaviour.

The Unity and Diversity of Executive Functions and Their Contributions to Complex “Frontal Lobe” Tasks: A Latent Variable Analysis

The results suggest that it is important to recognize both the unity and diversity ofExecutive functions and that latent variable analysis is a useful approach to studying the organization and roles of executive functions.

Adult age differences in goal activation and goal maintenance

According to the goal-neglect hypothesis of age-related decrements in cognitive control advocated in this paper, such decrements can be usefully and parsimoniously attributed to a reduced capacity

Conflict monitoring and cognitive control.

Two computational modeling studies are reported, serving to articulate the conflict monitoring hypothesis and examine its implications, including a feedback loop connecting conflict monitoring to cognitive control, and a number of important behavioral phenomena.

Response-inhibition deficits in obsessive-compulsive disorder: an indicator of dysfunction in frontostriatal circuits.

A basic disturbance of neurobehavioral inhibition in OCD may underlie the repetitive behavior that characterizes the illness and be related to abnormalities in orbital prefrontal ventral striatal circuits.

Deficits in strategy application following frontal lobe damage in man.

A quantitative investigation of the ability to carry out a variety of cognitive tasks was performed in patients who had sustained traumatic injuries which involved prefrontal structures, and it is argued that the problem arose from an inability to reactivate after a delay previously-generated intentions when they are not directly signalled by the stimulus situation.

Inhibitory inefficiency and failures of intention activation: age-related decline in the control of saccadic eye movements.

The results suggest that the notion of selective preservation with age of the ability to inhibit spatial responses does not apply to the active inhibition of prepotent spatial responses.
...