A glycolytic metabolon in Saccharomyces cerevisiae is stabilized by F-actin.

@article{AraizaOlivera2013AGM,
  title={A glycolytic metabolon in Saccharomyces cerevisiae is stabilized by F-actin.},
  author={Daniela Araiza-Olivera and Natalia Chiquete-F{\'e}lix and M{\'o}nica Rosas-Lemus and Jos{\'e} G Sampedro and Antonio Pe{\~n}a and Adela M{\'u}jica and Salvador Uribe-Carvajal},
  journal={The FEBS journal},
  year={2013},
  volume={280 16},
  pages={3887-905}
}
In the Saccharomyces cerevisiae glycolytic pathway, 11 enzymes catalyze the stepwise conversion of glucose to two molecules of ethanol plus two CO₂ molecules. In the highly crowded cytoplasm, this pathway would be very inefficient if it were dependent on substrate/enzyme diffusion. Therefore, the existence of a multi-enzymatic glycolytic complex has been suggested. This complex probably uses the cytoskeleton to stabilize the interaction of the various enzymes. Here, the role of filamentous… CONTINUE READING
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