A glucose transporter chimera confers a dominant negative glucose starvation phenotype in Saccharomyces cerevisiae.

@article{Sherwood2000AGT,
  title={A glucose transporter chimera confers a dominant negative glucose starvation phenotype in Saccharomyces cerevisiae.},
  author={Peter W. Sherwood and Iskra Katic and Pascual Sanz and M. Carlson},
  journal={Genetics},
  year={2000},
  volume={155 2},
  pages={989-92}
}
A family of glucose transporters mediates glucose uptake in Saccharomyces cerevisiae. We show that the dominant mutation GSF4-1, which impairs glucose repression of SUC2, results in a nonfunctional chimera of the transporters Hxt1p and Hxt4p. Hxt1/4p inhibits the function of wild-type glucose transporters. Similar mutations may facilitate analysis of the major facilitator superfamily. 

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