A globin for the brain.

  title={A globin for the brain.},
  author={Maurizio Brunori and Beatrice Vallone},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  volume={20 13},
The discovery that a myoglobin-like hemeprotein (called neuroglobin) is expressed in our brain raised considerable curiosity from the standpoints of biochemistry and pathophysiology alike. Neuroglobin is involved in neuroprotection from damage due to hypoxia or ischemia in vitro and in vivo; overexpression of neuroglobin ameliorates the recovery from stroke in experimental animals. The mechanism underlying this remarkable effect is still mysterious. Structural studies revealed that neuroglobin… CONTINUE READING


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