A global downregulation of microRNAs occurs in human quiescent satellite cells during myogenesis.

@article{Koning2012AGD,
  title={A global downregulation of microRNAs occurs in human quiescent satellite cells during myogenesis.},
  author={Merel Koning and Paul M. N. Werker and Marja J A van Luyn and Guido Krenning and Martin C Harmsen},
  journal={Differentiation; research in biological diversity},
  year={2012},
  volume={84 4},
  pages={314-21}
}
During myogenesis, human satellite cells differentiate and form multinucleated myotubes, while a fraction of the human satellite cells enter quiescence. These quiescent satellite cells are able to activate, proliferate and contribute to muscle regeneration. Post-transcriptional regulation of myogenesis occurs through specific myogenic microRNAs, also known as myomiRs. Although many microRNAs are involved in myotube formation, little is known on the involvement of microRNAs in satellite cells… CONTINUE READING
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