A global assay of haemostasis which uses recombinant tissue factor and tissue-type plasminogen activator to measure the rate of fibrin formation and fibrin degradation in plasma.

@article{He2007AGA,
  title={A global assay of haemostasis which uses recombinant tissue factor and tissue-type plasminogen activator to measure the rate of fibrin formation and fibrin degradation in plasma.},
  author={Shu Mei He and Kun Zhu and Mika Skeppholm and Jenny B{\"a}cklund Vedin and Jan E Svensson and Nils Egberg and Margareta Blomb{\"a}ck and H. Groemer L. J. Wallen},
  journal={Thrombosis and haemostasis},
  year={2007},
  volume={98 4},
  pages={871-82}
}
The global assay of Overall Haemostasis Potential we previously described has been refined. The coagulation cascade in platelet-poor plasma is triggered by adding a minimal dose of recombinant tissue factor together with purified phospholipids and calcium; fibrinolysis is initiated by adding recombinant tissue type-plasminogen activator in a concentration similar to what can be obtained during thrombolysis. Numerical differentials of optical densities reflecting rates of fibrin formation and… CONTINUE READING
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