A global analysis of peptide fragmentation variability.

@article{Barsnes2011AGA,
  title={A global analysis of peptide fragmentation variability.},
  author={Harald Barsnes and Ingvar Eidhammer and Lennart Martens},
  journal={Proteomics},
  year={2011},
  volume={11 6},
  pages={
          1181-8
        }
}
Understanding the fragmentation process in MS/MS experiments is vital when trying to validate the results of such experiments, and one way of improving our understanding is to analyze existing data. We here present our findings from an analysis of a large and diverse data set of MS/MS-based peptide identifications, in which each peptide has been identified from multiple spectra, recorded on two commonly used types of electrospray instruments. By analyzing these data we were able to study… CONTINUE READING
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