A global analysis of evolutionary conservation among known and predicted gammaherpesvirus microRNAs.

@article{Walz2010AGA,
  title={A global analysis of evolutionary conservation among known and predicted gammaherpesvirus microRNAs.},
  author={Nicole Walz and Thomas Christalla and Uwe Tessmer and Adam Grundhoff},
  journal={Journal of virology},
  year={2010},
  volume={84 2},
  pages={
          716-28
        }
}
MicroRNAs (miRNAs) are small, noncoding RNAs which posttranscriptionally regulate gene expression. The current release of the miRNA registry lists 16 viruses which encode a total of 146 miRNA hairpins. Strikingly, 139 of these are encoded by members of the herpesvirus family, suggesting an important role for miRNAs in the herpesvirus life cycle. However, with the exception of 7 miRNA hairpins known to be shared by Epstein-Barr virus (EBV) and the closely related rhesus lymphocryptovirus (rLCV… CONTINUE READING
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