A gist of gastrointestinal stromal tumors: A review.

  title={A gist of gastrointestinal stromal tumors: A review.},
  author={Ashwin Rammohan and Jeswanth Sathyanesan and Kamalakannan Rajendran and Anbalagan Pitchaimuthu and Senthil-Kumar Perumal and Uppili Srinivasan and Ravi Sivaperumal Ramasamy and Ravichandran Palaniappan and Manoharan Govindan},
  journal={World journal of gastrointestinal oncology},
  volume={5 6},
Gastrointestinal stromal tumors (GISTs) have been recognized as a biologically distinctive tumor type, different from smooth muscle and neural tumors of the gastrointestinal tract (GIT). They constitute the majority of gastrointestinal mesenchymal tumors of the GIT and are known to be refractory to conventional chemotherapy or radiation. They are defined and diagnosed by the expression of a proto-oncogene protein detected by immunohistochemistry which serves as a crucial diagnostic and… CONTINUE READING
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