A ghrelin gene variant may predict crossover rate from restricting-type anorexia nervosa to other phenotypes of eating disorders: a retrospective survival analysis.

@article{Ando2010AGG,
  title={A ghrelin gene variant may predict crossover rate from restricting-type anorexia nervosa to other phenotypes of eating disorders: a retrospective survival analysis.},
  author={Tetsuya Ando and Gen Komaki and Hiroki Nishimura and Tetsuro Naruo and Kenjiro Okabe and Keisuke Kawai and Masato Takii and Takakazu Oka and Naoki Kodama and Chiemi Nakamoto and Toshio Kariya Ishikawa and Mari Suzuki-Hotta and Kazunori Minatozaki and Chikara Yamaguchi and Aya Nishizono-Maher and Masaki Kono and Sohei Kajiwara and Hiroyuki Suematsu and Yuichiro Tomita and Shoichi Ebana and Yuri Okamoto and Katsutaro Nagata and Yoshikatsu Nakai and Masanori Koide and Nobuyuki Kobayashi and Nobuo Kurokawa and Toshiyasu Nagata and Nobuo Kiriike and Yoshito Takenaka and Kiyohide Nagamine and Kazuyoshi Ookuma and Shiho Murata},
  journal={Psychiatric genetics},
  year={2010},
  volume={20 4},
  pages={
          153-9
        }
}
BACKGROUND Patients with anorexia nervosa restricting type (AN-R) often develop bulimic symptoms and crossover to AN-binge eating/purging type (AN-BP), or to bulimia nervosa (BN). We have reported earlier that genetic variants of an orexigenic peptide ghrelin are associated with BN. Here, the relationship between a ghrelin gene variant and the rate of change from AN-R to other phenotypes of eating disorders (EDs) was investigated. METHODS Participants were 165 patients with ED, initially… CONTINUE READING
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