A genomics approach to the detection of positive selection in cattle: adaptive evolution of the T-cell and natural killer cell-surface protein CD2.

@article{Lynn2005AGA,
  title={A genomics approach to the detection of positive selection in cattle: adaptive evolution of the T-cell and natural killer cell-surface protein CD2.},
  author={David J. Lynn and Abigail R Freeman and Caitriona Murray and Daniel G Bradley},
  journal={Genetics},
  year={2005},
  volume={170 3},
  pages={1189-96}
}
The detection of adaptive evolution at the molecular level is of interest not only as an insight into the process of evolution but also because of its functional implications for genes of interest. Here, we present the first genomics approach to detecting positive selection operating on the Bos taurus lineage, an important domestic species. This analysis led to the identification of the T-cell and natural killer (NK) cell receptor cluster of differentiation 2 (CD2) as having a strong signal of… CONTINUE READING
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