A genomics approach reveals insights into the importance of gene losses for mammalian adaptations

@inproceedings{Sharma2018AGA,
  title={A genomics approach reveals insights into the importance of gene losses for mammalian adaptations},
  author={Virag Sharma and Nikolai Hecker and Juliana G. Roscito and Leo Foerster and Bjoern E. Langer and Michael Hiller},
  booktitle={Nature Communications},
  year={2018}
}
Identifying the genomic changes that underlie phenotypic adaptations is a key challenge in evolutionary biology and genomics. Loss of protein-coding genes is one type of genomic change with the potential to affect phenotypic evolution. Here, we develop a genomics approach to accurately detect gene losses and investigate their importance for adaptive evolution in mammals. We discover a number of gene losses that likely contributed to morphological, physiological, and metabolic adaptations in… CONTINUE READING
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Showing 1-10 of 72 references

principal isoforms for multiple gene sets

  • Rodriguez, J. M. et al. APPRIS 2017
  • Nucleic Acids Res. 46, D213–D217
  • 2018

community knowledge resource for the laboratory mouse

  • Blake, J. A. et al. Mouse Genome Database -2017
  • Nucleic Acids Res. 45, D723–D729
  • 2017

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